| Date | Location | Result | |
| 02-15-10 | Bluffton (SC) High School | Bluffton Lady Bobcats 60, North Myrtle Beach Lady Chiefs 43 | |
| 02-11-10 | North Myrtle Beach (SC) High School | Myrtle Beach Lady Seahawks 73, North Myrtle Beach Lady Chiefs 41 | |
| 02-09-10 | Socastee High School (Myrtle Beach, SC) | North Myrtle Beach Lady Chiefs 48, Socastee Lady Braves 44 | |
| 02-05-10 | Georgetown (SC) High School | North Myrtle Beach Lady Chiefs 48, Georgetown Lady Bulldogs 23 | |
| 02-02-10 | North Myrtle Beach (SC) High School | Lake City Lady Panthers 47, North Myrtle Beach Lady Chiefs 40 | |
| 01-29-10 | North Myrtle Beach (SC) High School | North Myrtle Beach Lady Chiefs 47, St. James Lady Sharks 39 | |
| 01-26-10 | North Myrtle Beach (SC) High School | North Myrtle Beach Lady Chiefs 41, Socastee Lady Braves 38 | |
| 01-22-10 | Myrtle Beach (SC) High School | Myrtle Beach Lady Seahawks 70, North Myrtle Beach Lady Chiefs 32 | |
| 01-19-10 | North Myrtle Beach (SC) High School | North Myrtle Beach Lady Chiefs 55, Georgetown Lady Bulldogs 36 | |
| 01-15-10 | Lake City (SC) High School | Lake City Lady Panthers 49, North Myrtle Beach Lady Chiefs 39 | |
| 01-12-10 | St. James High School | St. James Lady Sharks 43, North Myrtle Beach Lady Chiefs 33 | |
| 01-08-10 | North Myrtle Beach (SC) High School | North Myrtle Beach Lady Chiefs 57, South Brunswick Lady Cougars 16 | |
| 01-05-10 | North Myrtle Beach (SC) High School | North Myrtle Beach Lady Chiefs 53, Loris Lady Lions 45 | |
| 12-30-09 | South Florence (SC) High School | North Myrtle Beach Lady Chiefs 51, Clover 50 | |
| 12-29-09 | South Florence (SC) High School | Wilson 57, North Myrtle Beach Lady Chiefs 35 | |
| 12-28-09 | South Florence (SC) High School | North Myrtle Beach Lady Chiefs 62, West Florence 55 | |
| 12-23-09 | North Myrtle Beach (SC) High School | North Myrtle Beach Lady Chiefs 58, Boiling Springs 29 | |
| 12-22-09 | North Myrtle Beach (SC) High School | Wilson 74, North Myrtle Beach Lady Chiefs 47 | |
| 12-21-09 | North Myrtle Beach (SC) High School | Clover 39, North Myrtle Beach Lady Chiefs 31 | |
| 12-18-09 | North Myrtle Beach (SC) High School | Carolina Forest Lady Panthers 56, North Myrtle Beach Lady Chiefs 46 | |
| 12-16-09 | South Brunswick (NC) High School | North Myrtle Beach Lady Chiefs 46, South Brunswick Lady Cougars 30 | |
| 12-08-09 | West Brunswick (NC) High School | West Brunswick Lady Trojans 59, North Myrtle Beach Lady Chiefs 31 | |
| 12-04-09 | Carolina Fiorest High School | Carolina Forest Lady Panthers 59, North Myrtle Beach Lady Chiefs 27 | |
| 12-03-09 | Loris (SC) High School | North Myrtle Beach Lady Chiefs 52, Loris Lady Lions 27 | |
| 12-01-09 | North Myrtle Beach (SC) High School | West Brunswick Lady Trojans 42, North Myrtle Beach Lady Chiefs 25 | Box score |